Some common lymphocyte disorders are:

🔅 Lymphocytosis

– This is a condition where the lymphocyte count is higher than normal, which can indicate an infection, inflammation, or cancer. Lymphocytosis can be caused by:

Viral infections, such as Epstein-Barr virus, cytomegalovirus, or influenza;

Bacterial infections, such as whooping cough;

Parasitic infections, such as malaria;

Autoimmune diseases, such as rheumatoid arthritis or lupus;

Allergic reactions to medications;

Stress related to a medical emergency;

Smoking; or

Removal of the spleen.

– Lymphocytosis can also be a sign of blood cancers, such as chronic lymphocytic leukemia, acute lymphoblastic leukemia, or non-Hodgkin lymphoma.

🔅 Lymphocytopenia

– This is a condition where the lymphocyte count is lower than normal, which can increase the risk of infections and diseases. Lymphocytopenia can be caused by:

Inherited disorders, such as DiGeorge syndrome or Wiskott-Aldrich syndrome;

Acquired disorders, such as HIV infection, AIDS, or tuberculosis;

Medications that suppress the immune system, such as corticosteroids, chemotherapy, or radiation therapy;

Malnutrition or starvation; or

Autoimmune diseases, such as lupus or rheumatoid arthritis.

🔅 Lymphoproliferative disorders:

– These are a group of conditions where the lymphocytes grow and multiply abnormally, causing tumors or enlarged lymph nodes. Lymphoproliferative disorders can be benign (noncancerous) or malignant (cancerous).

– Some examples of lymphoproliferative disorders are follicular lymphoma, hairy cell leukemia, hemophagocytic lymphohistiocytosis (HLH), and large granular lymphocytic leukemia